| Uni-Pros-Trol 60 Capsules |
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Uni-Pros-Trol 60 Capsules
Item # DGL83910-60X
Manufactured by: Douglas Laboratories
Health Function:
Price:
$60.20 ($51.17 after 15% off)
Also available:
Ultra Uni-Pros-Trol 60 Capsules
$65.60 $52.48
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Uni-Pros-Trol™ capsules provided by Douglas
Laboratories provides 160 mg standardized Saw
Palmetto extract, 120 mg standardized Nettle extract,
and 50 mg standardized Pygeum extract combined
with other nutrients important for the healthy
function of the prostate gland and urinary tract.
Each Capsule Contains:
Vitamin E.....................................................100 IU
(as d-alpha-tocopheryl succinate)
Zinc (from Zinc Picolinate) .............................5 mg
Selenium (from Selenium Krebs) ..................25 mcg
Saw Palmetto extract (berry) .......................160 mg
Nettle extract (leaf)......................................120 mg
(standardized to 1% silicic acid)
Pygeum africanum (bark) ..............................50 mg
(standardized to 2% total sterols)
Beta-sistosterol ..............................................50 mg
L-Glycine.......................................................25 mg
L-Alanine.......................................................25 mg
L-Glutamic Acid............................................25 mg
Proanthocyanidins ......................................12.5 mg
Pyridoxal-5-Phosphate..................................7.5 mg
Lycopene complex........................................1.5 mg
Ginkgo biloba extract ....................................20 mg
(standardized to 24% ginkgoflavonglycosides
and 6% terpene lactones)
Pumpkin Seed Powder...................................50 mg
Who May Use
Uni-Pros-Trol™ capsules may be a useful dietary
adjunct for those men who wish to help maintain
healthy prostate function.
Suggested Usage
Two capsules per day or as directed by a physician.
FUNCTIONS
As men age, the function of their prostate gland tends
to change. This change during the normal aging
process can cause alterations in the functioning of
urinary health, including hesitancy, urgency, and
increased frequency of urination.
Studies indicate that saw palmetto may be able to inhibit
the conversion of testosterone to its more active and
potentially deleterious form, dihydrotestosterone (DHT),
via inhibition of alpha-5-reductase. Saw palmetto not
only inhibits the binding of DHT to cellular receptors, but
also has alpha1-adrenoceptor-inhibitory properties.
Alpha1-adrenoceptor antagonism may be responsible for
saw palmetto's ability to provide support to the urinary
tract and prostate. Saw palmetto extracts have also been
found to inhibit the biosynthesis of proinflammatory
prostaglandins and leukotrienes.
Pygeum extract can decrease prolactin and cholesterol
levels in the prostate, which in turn can decrease uptake
and reduce the number of binding sites for testosterone in
the prostate. In addition, pygeum extract, like saw
palmetto, interferes with the synthesis of proinflammatory
prostaglandins. Pumpkin seed and nettles are thought to
have similar properties.
Other nutrients have also shown promise for prostate
health. Phytosterols, such as those found in extracts
of pumpkin seeds have demonstrated positive effects
on urine flow, and frequency of urination. Zinc has
also been shown to be intricately involved in prostate
health and metabolism. Zinc accumulates in the
mitochondria of prostate cells and effects the
oxidation of citric acid. This in turn effects the Krebs
cycle and the ability of the cell to produce energy. It
is believed that this decrease in the prostate's ability
to produce energy can lead to an inhibition of
proliferation. Additionally, zinc may modify prostate
specific antigen (PSA) levels. PSA has the ability to
cleave certain proteins that bind insulin-like growth
factor-I (IGF-I). These proteins then lose some of
their ability to bind IGF-I, leaving greater amounts of
circulating IGF-I, which in turn can effect the
proliferation of certain tissues. Consequently,
modifying PSA may lead to less IGF-I available to
effect the prostate. Nutrients such as vitamin B6,
selenium, vitamin E, lycopene and certain amino
acids also appear to play an important role in
maintaining proper prostate function.
Side Effects
None reported.
Storage
Store in a cool, dry place, away from direct light. Keep out of reach of
children.
REFERENCE
-
Briley, M., Carilla, E., Roger, A. et al. A new treatment of
prostatic hyperplasia. Permixon® has antiandrogen effects at two
complementary levels. New Trends Androlog Sci (1985);1:24-26.
-
Carilla, E., Roger A., Briley, M. et al. The lipido-sterolic extract
of Serenoa repens B: new treatment of prostatic hyperplasia, with
antiandrogen effects at two complementary levels. Exerpta Medica
(1986);216-223.
-
Carraro, J. C., Raynaud, J.P., Koch, G. et al. Comparison of
phytotherapy (Permixon®) with finasteride in the treatment of
benign prostate hyperplasia: a randomized international study of
1098 patients. Prostate (1996);29:231-40.
-
Champault, G., Patel, J. C., Bonard, A. M. A double-blind trial of
an extract of the plant Serenoa repens in benign prostatic
hyperplasia. Br J Clin Pharmacol (1984);18:461-462.
-
Chatelain, C., Autet, W., Brachman, F. (1999) Comparison of
once and twice daily dosage forms of Pygeum africanum extract in
patients with benign prostatic hyperplasia: a randomized, doubleblind
study, with long-term open label extension. Urology
(1999);54:473-478.
-
Costello, L. C., Franklin, R. B. Novel role of zinc in the regulation
of prostate citrate metabolism and its implications in prostate
cancer. Prostate (1998);35:285-96.
-
Cukier, Ducassou, Le Guillou, et al. Seronoa repens extract vs.
placebo. C R Ther Pharmacol Clin 4:15-21.
-
Descotes, j. L., Rambeaud J. J., Deschaseaux, P. et al. Placebocontrolled
evaluation of the efficacy and tolerability of Permixon®
in benign prostatic hyperplasia after exclusion of placebo
responders. Clin Drug Invest (1995);9:291-297.
-
Grasso, M., Montesano A., Bounaguidi A. et al. Comparative
effects of alfuzosin versus Serenoa repens in the treatment of
symptomatic benign prosatic hyperplasia. Arch Esp Urol
(1995);48:97-103.
-
Hardell, L., Degerman, A., Tomic, R., Marklund, S. L., Bergfors,
M. Levels of selenium in plasma and glutathione peroxidase in
erythrocytes in patients with prostate cancer or benign hyperplasia.
Eur J Cancer Prev (1995);4:91-95.
-
Lichius, J. J., Muth, C. The inhibiting effects of Urtica dioica root
extracts on experimentally induced prostatic hyperplasia in the
mouse. Planta Med (1997);63:307-310.
-
Plosker, G. L., Brogden, R. N. Seronoa repens (Permixon®) a
review of its pharmacology and therapeutic efficacy in Benign
prostatic hyperplasia. Drugs Aging (1996);9:379-395.
-
Sutkowski, D. M., Goode, R. L., Teater, A. M., et al. Growth
regulation of prostatic stromal cells by prostate specific antigen.
J Natl Cancer Inst (1999);91:1663-1669.
-
Yablonsky, F., Nicolas, V., Riffaud, J. P., Bellamy, F.
Antiproliferative effect of Pygeum africanum extract on rat
prostatic fibroblasts. J Urol (1997);157:2381-2387.
* These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
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