| Uni-Pros-Trol 30 Capsules |
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Uni-Pros-Trol 30 Capsules
Item # DGL83910-30X
Health Function: Price: $32.50 ($26.00 after 20% off)
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Uni-Pros-Trol™ capsules provided by Douglas Laboratories provides 160 mg standardized Saw Palmetto extract, 120 mg standardized Nettle extract, and 50 mg standardized Pygeum extract combined with other nutrients important for the healthy function of the prostate gland and urinary tract.
Each Capsule Contains:
Vitamin E.....................................................100 IU
(as d-alpha-tocopheryl succinate)
Zinc (from Zinc Picolinate) .............................5 mg
Selenium (from Selenium Krebs) ..................25 mcg
Saw Palmetto extract (berry) .......................160 mg
Nettle extract (leaf)......................................120 mg
(standardized to 1% silicic acid)
Pygeum africanum (bark) ..............................50 mg
(standardized to 2% total sterols)
Beta-sistosterol ..............................................50 mg
L-Glycine.......................................................25 mg
L-Alanine.......................................................25 mg
L-Glutamic Acid............................................25 mg
Proanthocyanidins ......................................12.5 mg
Pyridoxal-5-Phosphate..................................7.5 mg
Lycopene complex........................................1.5 mg
Ginkgo biloba extract ....................................20 mg
(standardized to 24% ginkgoflavonglycosides
and 6% terpene lactones)
Pumpkin Seed Powder...................................50 mg
Who May Use
Uni-Pros-Trol™ capsules may be a useful dietary adjunct for those men who wish to help maintain healthy prostate function.
Suggested Usage
Two capsules per day or as directed by a physician.
FUNCTIONS
As men age, the function of their prostate gland tends to change. This change during the normal aging process can cause alterations in the functioning of urinary health, including hesitancy, urgency, and increased frequency of urination.
Studies indicate that saw palmetto may be able to inhibit the conversion of testosterone to its more active and potentially deleterious form, dihydrotestosterone (DHT), via inhibition of alpha-5-reductase. Saw palmetto not only inhibits the binding of DHT to cellular receptors, but also has alpha1-adrenoceptor-inhibitory properties. Alpha1-adrenoceptor antagonism may be responsible for saw palmetto's ability to provide support to the urinary tract and prostate. Saw palmetto extracts have also been found to inhibit the biosynthesis of proinflammatory prostaglandins and leukotrienes.
Pygeum extract can decrease prolactin and cholesterol levels in the prostate, which in turn can decrease uptake and reduce the number of binding sites for testosterone in the prostate. In addition, pygeum extract, like saw palmetto, interferes with the synthesis of proinflammatory prostaglandins. Pumpkin seed and nettles are thought to have similar properties.
Other nutrients have also shown promise for prostate health. Phytosterols, such as those found in extracts of pumpkin seeds have demonstrated positive effects on urine flow, and frequency of urination. Zinc has also been shown to be intricately involved in prostate health and metabolism. Zinc accumulates in the mitochondria of prostate cells and effects the oxidation of citric acid. This in turn effects the Krebs cycle and the ability of the cell to produce energy. It is believed that this decrease in the prostate's ability to produce energy can lead to an inhibition of proliferation. Additionally, zinc may modify prostate specific antigen (PSA) levels. PSA has the ability to cleave certain proteins that bind insulin-like growth factor-I (IGF-I). These proteins then lose some of their ability to bind IGF-I, leaving greater amounts of circulating IGF-I, which in turn can effect the proliferation of certain tissues. Consequently, modifying PSA may lead to less IGF-I available to effect the prostate. Nutrients such as vitamin B6, selenium, vitamin E, lycopene and certain amino acids also appear to play an important role in maintaining proper prostate function.
Side Effects
None reported.
Storage
Store in a cool, dry place, away from direct light. Keep out of reach of children.
REFERENCE
- Briley, M., Carilla, E., Roger, A. et al. A new treatment of prostatic hyperplasia. Permixon® has antiandrogen effects at two complementary levels. New Trends Androlog Sci (1985);1:24-26.
- Carilla, E., Roger A., Briley, M. et al. The lipido-sterolic extract of Serenoa repens B: new treatment of prostatic hyperplasia, with antiandrogen effects at two complementary levels. Exerpta Medica (1986);216-223.
- Carraro, J. C., Raynaud, J.P., Koch, G. et al. Comparison of phytotherapy (Permixon®) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1098 patients. Prostate (1996);29:231-40.
- Champault, G., Patel, J. C., Bonard, A. M. A double-blind trial of an extract of the plant Serenoa repens in benign prostatic hyperplasia. Br J Clin Pharmacol (1984);18:461-462.
- Chatelain, C., Autet, W., Brachman, F. (1999) Comparison of once and twice daily dosage forms of Pygeum africanum extract in patients with benign prostatic hyperplasia: a randomized, doubleblind study, with long-term open label extension. Urology (1999);54:473-478.
- Costello, L. C., Franklin, R. B. Novel role of zinc in the regulation of prostate citrate metabolism and its implications in prostate cancer. Prostate (1998);35:285-96.
- Cukier, Ducassou, Le Guillou, et al. Seronoa repens extract vs. placebo. C R Ther Pharmacol Clin 4:15-21.
- Descotes, j. L., Rambeaud J. J., Deschaseaux, P. et al. Placebocontrolled evaluation of the efficacy and tolerability of Permixon® in benign prostatic hyperplasia after exclusion of placebo responders. Clin Drug Invest (1995);9:291-297.
- Grasso, M., Montesano A., Bounaguidi A. et al. Comparative effects of alfuzosin versus Serenoa repens in the treatment of symptomatic benign prosatic hyperplasia. Arch Esp Urol (1995);48:97-103.
- Hardell, L., Degerman, A., Tomic, R., Marklund, S. L., Bergfors, M. Levels of selenium in plasma and glutathione peroxidase in erythrocytes in patients with prostate cancer or benign hyperplasia. Eur J Cancer Prev (1995);4:91-95.
- Lichius, J. J., Muth, C. The inhibiting effects of Urtica dioica root extracts on experimentally induced prostatic hyperplasia in the mouse. Planta Med (1997);63:307-310.
- Plosker, G. L., Brogden, R. N. Seronoa repens (Permixon®) a review of its pharmacology and therapeutic efficacy in Benign prostatic hyperplasia. Drugs Aging (1996);9:379-395.
- Sutkowski, D. M., Goode, R. L., Teater, A. M., et al. Growth regulation of prostatic stromal cells by prostate specific antigen. J Natl Cancer Inst (1999);91:1663-1669.
- Yablonsky, F., Nicolas, V., Riffaud, J. P., Bellamy, F. Antiproliferative effect of Pygeum africanum extract on rat prostatic fibroblasts. J Urol (1997);157:2381-2387.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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